May
- May 1870 M.A. Forbes, bark, lost off Currituck Beach
- May 1, 1897 George M. Adams, schooner, lost off Nags Head
- May 2, 1900 Virginia, steamer, sunk off Cape Hatteras; 2 killed;
- May 4, 1874 Waltham, brig, lost off Bodie Island
- May 4, 1943 Panam, tanker, torpedoed and sunk by U-129; 2 killed
- May 5, 1901 Hettie J. Dorman, schooner, lost off Cape Hatteras
- May 5, 1942 Lady Drake, passenger-freighter, torpedoed and sunk by U-160; 12 killed
- May 6, 1853 Bladen McLaughlin, steamer, lost off Kitty Hawk
- May 6, 1942 HMS Senateur Duhamel, armed-trawler, collided with USS Semmes and sunk;
- May 7, 1864 Raleigh, confederate gunship, abandoned Cape Fear River
- May 8, 1845 Moon, brig, lost off Nags Head
- May 8, 1862 Oriental, federal transport, lost off Bodie Island
- May 8, 1903 Vera Cruz VII, brigatine, sunk off of Portsmouth Island; 1 killed
- May 9, 1905 D.D. Haskell, sunk off of Core Banks; 1 killed;
- May 9, 1942 U-352, submarine, depth-charged and sunk by USCG Icarus; 14 killed
- May 10, 1889 Aberlady Bay, steamer, lost off Lookout Shoals
- May 12, 1942 HMS Bedfordshire, armed-trawler, torpedoed and sunk by U-558; 37 killed
- May 14, 1844 Danube, schooner, lost off Bodie Island
- May 14, 1954 Omar Babun, freighter, ran aground off Rodanthe Beach
- May 15, 1890 Hattie S. Clark, schooner, lost off Cape Fear; 5 killed
- May 16, 1861 Oriental, steamer, stranded near Oregon Inlet
- May 20, 1908 George Weems, freighter, caught on fire and sunk;
- May 22, 1896 Glanayron, freighter, ran aground outer Diamond Shoals
- May 23, 1851 Aid Harrington, ship, lost off Caffey's Inlet
- May 24, 1921 Mary J. Haynie, schooner, lost off Ocracoke
- May 25, 1891 Vibilia, bark, lost off Poyner's Hill
- May 27, 1889 Viola W. Burton, schooner, lost off Big Kinnakeet
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